Sickle Cell Nephropathy

Sickle Cell Nephropathy

Sickle cell disease (SCD), is an autosomal recessive hemoglobin disorder that results from the replacement of glutamate for valine at the sixth amino acid of the beta-globin chain. This replacement results in the formation of hemoglobin S (HbS) tetramers that accumulate during oxidative stress, tissue hypoxia, or dehydration. The consequence of this is red blood cell sickling, early destruction of erythrocytes, and widespread vaso-occlusive episodes (VOC), subsequently causing multiorgan damage. Sickle cell nephropathy (SCN) is a group of renal complications that include hematuria, proteinuria, hyposthenuria, renal papillary necrosis, renal tubular disorders, acute and chronic kidney injury, sickle cell glomerulopathy, and renal medullary carcinoma. This activity illustrates the evaluation and treatment of sickle cell nephropathy and explains the role of the interprofessional team in managing patients with this condition.

  • Provider:StatPearls, LLC
  • Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/29016
  • Start Date: 2023-09-01 05:00:00
  • End Date: 2023-09-01 05:00:00
  • Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
    Nursing: 1.0 hours
    Pharmacy: 1.0 hours
  • MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
    ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
    ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
    ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
    ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
    ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
  • Commercial Support: No
  • Activity Type: Enduring Material
  • CME Finder Type: Online Learning
  • Fee to Participate: Variable
  • Measured Outcome: Learner Knowledge, Learner/Team Competence
  • Provider Ship: Directly Provided
  • Registration: Open to all
  • Specialty: Adolescent Medicine, Advanced Heart Failure and Transplant Cardiology, Ambulatory/Outpatient, Cardiovascular Disease, Chemical Pathology, Clinical Pathology, Critical Care Medicine, Developmental-Behavioral Pediatrics, Endocrinology, Diabetes, and Metabolism, Gastroenterology, General Operative Anesthesia, General Pediatrics, General Surgery, Hematology, Hematology (Blood, BM), Hospital Medicine, Infectious Disease, Internal Medicine, Neonatal-Perinatal Medicine, Nephrology, Neurocritical Care, Neurodevelopmental Disabilities, Pediatric Anesthesia, Pediatric Cardiology, Pediatric Critical Care Medicine, Pediatric Emergency Medicine, Pediatric Endocrinology, Pediatric Gastroenterology, Pediatric Hematology-Oncology, Pediatric Infectious Diseases, Pediatric Nephrology, Pediatric Neurology, Pediatric Pulmonology, Pediatric Rheumatology, Pediatric Surgery, Pediatric Transplant Hepatology, Pulmonary Disease, Renal/Medical Renal, Sleep Medicine, Sports Medicine, Surgical Critical Care, Transplant Hepatology
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