Transthyretin-mediated amyloidosis (ATTR): successful identification and its role in optimizing outcomes

Transthyretin-mediated amyloidosis (ATTR): successful identification and its role in optimizing outcomes

In this online, self-learning activity:

Transthyretin-mediated amyloidosis (ATTR) is a progressive, multisystem, life-threatening disorder characterized by the extracellular deposition of misfolded, insoluble amyloid fibrils. The role of the TTR protein is to transport thyroxine and retinol-binding proteins, and it is vital for cognition, nerve regeneration, and axonal growth. TTR itself is innately amyloidogenic even without the presence of genetic mutations, which may account for wild-type ATTR (wtATTR), while a hereditary form of ATTR (hATTR) may be passed to offspring through autosomal dominant inheritance. Left untreated, the average life expectancy of ATTR is 3 to 15 years from symptom onset.

  • Provider:ScientiaCME
  • Activity Link: https://www.scientiacme.org/cme-509-111-0-1-1-attr-cme
  • Start Date: 2023-12-15 06:00:00
  • End Date: 2023-12-15 06:00:00
  • Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
  • MOC Credit Details: ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
  • Commercial Support: Source: Alnylam Pharmaceutical - Amount: 15000.0 - Is Kind Support: False
  • Activity Type: Enduring Material
  • CME Finder Type: Online Learning
  • Fee to Participate: No, it's free
  • Measured Outcome: Learner Competence, Learner Knowledge, Learner Performance
  • Provider Ship: Directly Provided
  • Registration: Open to all
  • Specialty: Cardiovascular Disease, Hematology
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