Trastuzumab is an FDA-approved antineoplastic biologic that targets HER2-positive breast and gastric cancer. This activity outlines trastuzumab’s various indications and off-label uses, including its combination with anthracycline or taxane-based chemotherapy for breast cancer, as monotherapy or in combination with paclitaxel for metastatic breast cancer, and in combination with cisplatin-based chemotherapy for gastric cancer. This discussion also includes the mechanism of action, administration methods, significant adverse effects, FDA-issued box warnings, toxicity profile, and monitoring requirements of trastuzumab. Understanding these elements is crucial for tailoring therapy to meet patient needs, optimizing dosing regimens, and minimizing adverse reactions.The activity also highlights the critical role of the interprofessional healthcare team in effectively managing conditions that trastuzumab is prescribed to treat. Knowledge of trastuzumab’s pharmacology enables providers to make decisions that improve patient outcomes. Healthcare professionals are provided with the necessary scientific foundation to enhance patient care through targeted and personalized treatment strategies.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/30530
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.0 hours
Nursing: 1.0 hours
Pharmacy: 1.0 hours - MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
ABTS - 1.0 Point; Credit Type(s): Accredited CME (ABTS)
ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
ABTS - 1.0 Point; Credit Type(s): Self-Assessment (ABTS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Ambulatory/Outpatient, Clinical Pathology, Complex General Surgical Oncology, Gastroenterology, General Operative Anesthesia, General Surgery, Internal Medicine, Medical Oncology, Non-Thoracic Surgery