Tuberculous meningitis (TBM) manifests extrapulmonary tuberculosis caused by the seeding of the meninges with the bacilli of Mycobacterium tuberculosis (MTB). MTB is first introduced into the host by droplet inhalation infecting the alveolar macrophage. The primary infection localizes in the lung with dissemination to the lymph nodes. At this point in the infectious process, a high degree of bacteremia can seed the entire body. In TBM, the meninges are seeded by MTB and form subependymal collections called Rich foci. These foci can rupture into the subarachnoid space and cause an intense inflammatory response resulting in meningitis symptoms. The exudates caused by this response can encase cranial nerves and cause nerve palsies. They can entrap blood vessels, causing vasculitis, and block cerebral spinal fluid flow, leading to hydrocephalus. These immune responses can lead to complications associated with TBM and chronic sequela in patients who recover from TBM.Participants in this course gain critical knowledge on evaluating, managing, and preventing TBM, including the latest public health strategies to combat this global health challenge. The course focuses on enhancing the ability to diagnose TBM early and initiate appropriate treatment swiftly, including managing drug-resistant cases. By emphasizing the importance of interprofessional collaboration, the course demonstrates how coordinated efforts among infectious disease specialists, neurologists, public health professionals, and other healthcare professionals can significantly improve patient outcomes. This collaborative approach is crucial in reducing mortality rates and preventing long-term neurological complications in patients affected by TBM.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/30664
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: AMA PRA Category 1 Credit™️: 1.5 hours
Nursing: 1.5 hours
Pharmacy: 1.5 hours - MOC Credit Details: ABS - 1.5 Point; Credit Type(s): Accredited CME (ABS)
ABPATH - 1.5 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.5 Point; Credit Type(s): Lifelong Learning (ABA)
ABIM - 1.5 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.5 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.5 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Adolescent Medicine, Critical Care Medicine, General Operative Anesthesia, General Pediatrics, Hospital Medicine, Infectious Disease, Infectious Diseases/Medical Microbiology, Internal Medicine, Neurocritical Care, Neuropathology (incl. Neuromuscular), Pediatric Critical Care Medicine, Pediatric Emergency Medicine, Pediatric Infectious Diseases, Pediatric Neurology