Venlafaxine

Venlafaxine

Venlafaxine is categorized as a serotonin-norepinephrine reuptake inhibitor (SNRI). It is approved by the US Food and Drug Administration (FDA) to treat major depressive disorder (unipolar), social anxiety disorder, and panic disorder. In addition, venlafaxine is commonly used off-label for conditions such as attention-deficit disorder, fibromyalgia, diabetic neuropathy, complex pain syndromes, hot flashes, migraine prevention, posttraumatic stress disorder, obsessive-compulsive disorder, and premenstrual dysphoric disorder. Venlafaxine can be used either as a standalone treatment or as part of a combination therapy regimen with other medications.Venlafaxine increases serotonin and norepinephrine levels in the central nervous system by blocking transport proteins and inhibiting their reuptake at the presynaptic terminal. This leads to a greater availability of neurotransmitters at the synapse, ultimately enhancing the activation of postsynaptic receptors. Antidepressants such as venlafaxine enhance the expression of brain-derived neurotrophic factors and promote neuroplasticity, ultimately decreasing neuroinflammation. This activity focuses on the indications, mechanism of action, administration methods, significant adverse drug reactions, contraindications, and monitoring strategies of venlafaxine in the treatment of psychiatric disorders. This activity underscores how clinicians can direct patient therapy with evidence-based guidelines to achieve optimal treatment outcomes and patient satisfaction within the interprofessional healthcare team.

  • Provider:StatPearls, LLC
  • Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/31054
  • Start Date: 2023-09-01 05:00:00
  • End Date: 2023-09-01 05:00:00
  • Credit Details: IPCE Credits: 1.0 hours
    AMA PRA Category 1 Credit™️: 1.0 hours
    Nursing: 1.0 hours
    Pharmacy: 1.0 hours
  • MOC Credit Details: ABS - 1.0 Point; Credit Type(s): Accredited CME (ABS)
    ABPATH - 1.0 Point; Credit Type(s): Lifelong Learning (ABPATH)
    ABA - 1.0 Point; Credit Type(s): Lifelong Learning (ABA)
    ABIM - 1.0 Point; Credit Type(s): Medical Knowledge (ABIM)
    ABS - 1.0 Point; Credit Type(s): Self-Assessment (ABS)
    ABP - 1.0 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
  • Commercial Support: No
  • Activity Type: Enduring Material
  • CME Finder Type: Online Learning
  • Fee to Participate: Variable
  • Measured Outcome: Learner Knowledge, Learner/Team Competence
  • Provider Ship: Directly Provided
  • Registration: Open to all
  • Specialty: Adolescent Medicine, Ambulatory/Outpatient, Chemical Pathology, Child Abuse Pediatrics, Developmental-Behavioral Pediatrics, Endocrinology, Diabetes, and Metabolism, General Operative Anesthesia, General Pediatrics, General Surgery, Hospital Medicine, Internal Medicine, Medical Toxicology, Neurodevelopmental Disabilities, Pain Medicine, Pediatric Emergency Medicine, Rheumatology
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