Warfarin is a vitamin K antagonist used as an anticoagulant used for treatment and prevention of a variety of coagulopathic and thromboembolic disorders. While it was initially marketed as a rodenticide, it has been used as a medication for more than a half-century. Superwarfarins are now also used as pesticides and should be recognized as having potential to cause warfarin toxicity. They are one hundred times more potent than warfarin. Toxicity can occur due to intentional overdose, unintentional overdose, and pediatric ingestion. Intentional overdose has been noted to be relatively rare; a 25-year long survey involving 2 tertiary care centers with toxicology services reported a total of 22 intentional overdoses in adults. Unintentional overdose or toxicity can occur through various mechanisms such as during the initial dose titration phase, with changes in diet that affect the medication potency, due to interactions with other medications, or secondary to metastatic liver disease. This activity describes the pathophysiology of warfarin toxicity and highlights the role of the interprofessional team in its management.
- Provider:StatPearls, LLC
- Activity Link: https://www.statpearls.com/ArticleLibrary/viewarticle/30393
- Start Date: 2023-09-01 05:00:00
- End Date: 2023-09-01 05:00:00
- Credit Details: IPCE Credits: 1.5 hours
AMA PRA Category 1 Credit™️: 1.5 hours
Nursing: 1.5 hours
Pharmacy: 1.5 hours - MOC Credit Details: ABS - 1.5 Point; Credit Type(s): Accredited CME (ABS)
ABOS - 1.5 Point; Credit Type(s): Accredited CME (ABOS)
ABPATH - 1.5 Point; Credit Type(s): Lifelong Learning (ABPATH)
ABA - 1.5 Point; Credit Type(s): Lifelong Learning (ABA)
ABTS - 1.5 Point; Credit Type(s): Accredited CME (ABTS)
ABIM - 1.5 Point; Credit Type(s): Medical Knowledge (ABIM)
ABS - 1.5 Point; Credit Type(s): Self-Assessment (ABS)
ABP - 1.5 Point; Credit Type(s): Lifelong Learning and Self-Assessment (ABP)
ABTS - 1.5 Point; Credit Type(s): Self-Assessment (ABTS) - Commercial Support: No
- Activity Type: Enduring Material
- CME Finder Type: Online Learning
- Fee to Participate: Variable
- Measured Outcome: Learner Knowledge, Learner/Team Competence
- Provider Ship: Directly Provided
- Registration: Open to all
- Specialty: Adult Cardiac, Adult Congenital Heart Disease, Advanced Heart Failure and Transplant Cardiology, Ambulatory/Outpatient, Cardiothoracic, Cardiovascular, Cardiovascular Disease, Chemical Pathology, Critical Care, Critical Care Medicine, Forensic Pathology, General Operative Anesthesia, General Orthopaedics, General Pediatrics, General Surgery, General Thoracic, Geriatric Medicine, Hematology, Hematology (Blood, BM), Hospital Medicine, Internal Medicine, Medical Toxicology, Non-Thoracic Surgery, Pediatric Cardiology, Pediatric Critical Care Medicine, Pediatric Emergency Medicine, Pediatric Hematology-Oncology, Pediatric Pulmonology, Pulmonary Disease, Surgical Critical Care